Abstract:
Combined oral contraceptive pills (COCP) use, is link to the development of precancerous cervical lesions. There
are variations in reports across studied populations. Our study was a comparative, cross-sectional study. SPSS version 20
(IBM, Armonk, NY, USA) was used for data analysis and P-Value < 0.05 was considered statistically significant. The
Prevalence of precancerous cervical lesions in the Exposed and Control groups were 16.4% (9/55) and 14.5% (8/55)
respectively (P = of 0.79). In the exposed group, four out of the nine women that had abnormal cervical cytology results had
high grade squamous intra-epithelial lesions (HGSIL) while only one out of 8 women that had abnormal cytology results in the
control group had HGSIL. We found no significant difference in the prevalence of pre-cancerous cervical lesions between
users and non-users of COCP. However, women who used COCP had higher cases of HGSIL when compared with the control
group. Therefore, we suggest relatively short schedule of cervical cytology screening for this group of women relative to the
general population.
